Development of technology to distinguish and separate the handedness of molecules.
Keywords: Organic synthesis chemistry, chiral chemistry, optical resolution, organic crystals, supramolecular chemistry, liquid crystals, gels.
Just as humans have right-handed and left-handed preferences, the molecular world also contains right-handed and left-handed molecules (enantiomers). In applications such as food, pharmaceuticals, and fragrances, these left and right molecules can exhibit completely different effects, making the technology for separating mixtures into their respective enantiomers (optical resolution) important. While the technology of optical resolution has been known for a long time, systematic research on it is relatively scarce worldwide. Therefore, we are conducting research to make optical resolution a more user-friendly technology. For example, traditional methods often faced the problem of successfully obtaining only one type of molecule, either left or right. However, we have found a method that allows us to obtain both enantiomers simply by changing the solvent used. Additionally, we are working on developing methods to separate compounds that have been difficult to separate until now at a low cost, aiming to advance research towards methods that combine separation efficiency, versatility, and economic viability.
- 企業：埼玉大学 オープンイノベーションセンター
- 価格：Other
